Lunasin's ability to support cardiovascular health was acknowledged by the
American Heart Association at their Annual Scientific Session in November. 
Dr. Alfredo Galvez's presentation abstract was selected for publication in
the prestigious AHA Journal, Circulation!
 

View the abstract here.

Lunasin Technology in the News!
Nutrition Industry Executive, October 2012
Progress In the Cholesterol Puzzle

Read article

Cancer Research

Soy contains a variety of phytochemicals with demonstrated anticancer activity, including protease inhibitors, phytate, phytosterols, saponins, and isoflavones. Soybeans also contain bioactive proteins that exhibit anticancer activity including lectins and the most recently discovered peptide lunasin. By its involvement in allowing or denying access to genes for transcription, acetylation is pivotal in the process of turning genes on and off. Lunasin has a binding affinity for regions of nucleosomes that are not fully acetylated. The negatively charged amino acids of Lunasin have a natural attraction to positively charged amino acid in histones. During acetylation, the positive charge on histones is neutralized. When this occurs, genes involved in cell proliferation (e.g. oncogenes) are "turned on" or activated, resulting in tumors or cancer. Lunasin can bind to hypo­acetylated histones (histones that still have the positive charge) in different regions of chromosomes, blocking or preventing their acetylation. This blocking action helps keep cancer related genes switched "off".

The chromatin binding affinity of Lunasin is believed to be the underlying mechanism responsible for the cancer-preventing property of Lunasin. A series of studies strongly suggests that chromatin modification is linked with tumor suppression pathways. When delivered to the proper target tissue Lunasin may play a role in preventing or "silencing" the expression of genes that lead to tumor formation, intervening primarily at the initiation and promotion-and possibly other stages of carcinogenesis.

Related Links About Soybeans

Epigenetics: A New Frontier in Cancer Research

Soy Cream's Health Benefits

Your Genomic Diet



Soy Peptide Plus Chemo Drug Block Colon Cancer's Spread to Liver, Study Finds

 

Lunasin Mechanism of Action

Lunasin video Watch video of how Lunasin soy peptide works to lower cholesterol.


Cardiovascular Research


Cancer Research